CD20 is a transmembrane, non-glycosylated protein expressed on B-cell precursors andmature B cells, but is lost following differentiation into plasma cells. This antibody does notcross-react with non-hematopoetic neoplasms. CD20 (B-cell Pan) reacts with a membrane antigen that is present in B-cells. This antibody strongly recognizes Reed-Sternberg cells predominant in Hodgkin`s disease. Since no staining of histiocytes or plasma cells has been observed and CD20 has not been detected in T-cell malignancies, it is a very strong marker of B-cell lymphomas. B-cell, Panmarker recognizes a formalin resistant intracytoplasmic antigen
Intended Use: IVD
Antibody Type: Monoclonal
Clone: CD20/C23
Source: Mouse
Tissue Type/Cancer Type: Spleen