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Anti-CD20 (B cell)

SKU: AM238GP Categories: , , ,
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Product Description

This antibody reacts with a formalin-resistant intracytoplasmic epitope found in the majority of B cells which is now considered to be the CD20 antigen, a pan-B cell marker. The antibody primarily recognizes a 33 kD polypeptide B cell component and also a minor 30 kD cellular antigen. The staining pattern is consistent with pan-B reactivity, producing staining for B cells in lymphoid and peripheral blood tissue. This antibody intensely stains germinal centers and B immunoblasts in lymphoid tissue.The L26 antibody is widely regarded as the most selective B cell marker currently available. L26 has shown no cross-reactivity with nonlymphoid tissues. L26 may prove to be a useful marker for L&H variants of Reed-Sternberg cells of Hodgkin’s lymphomas where reactive pattern is distinct from other Reed-Sternberg variants

Intended Use

IVD

Antibody Type

Monoclonal

Clone

L-26

Source

Mouse

Tissue Type/Cancer Type

Tonsil

Pack

0.5 mL – Manual – Concentrate, 1 mL – Manual – Concentrate, 6 mL – Manual – RTU, 50 Tests – Automation – Xmatrx, 100 Tests – Automation – i6000, 200 Tests – Automation – Xmatrx, 5 slides – Xmatrx, 5 slides – Manual