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Anti-CD19

SKU: AN729GP Categories: , , ,
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Product Description

CD19 is a cell surface molecule that interacts with the antigen receptor of B lymphocytes in order to reduce the threshold for antigen receptor-dependent stimulation. CD19 is expressed on folliculare dendritic cells and B cells. In fact, it is present on B cells from earliest recognizable B-cell lineage cells during development to B-cell blasts but it absent on maturation of B-cell to plasma cells. It primarily acts as a B cell co-receptor in conjunction with CD21 and CD81. CD19 has been observed in lymphomas and leukemias but often weak/negative in follicular lymphoma or diffuse target B-cell lymphoma. CD19 is well-suited for formalin-fixed paraffin-embedded tissues, flow cytomentry and western blotting technique. CD19 can provide useful diagnositic informationation for the study of B lymphoproliferative disorders

Intended Use

IVD

Antibody Type

Monoclonal

Clone

EP169

Source

Rabbit

Tissue Type/Cancer Type

Tonsil

Pack

0.5 mL – Manual – Concentrate, 1 mL – Manual – Concentrate, 6 mL – Manual – RTU, 50 Tests – Automation – Xmatrx, 100 Tests – Automation – i6000, 200 Tests – Automation – Xmatrx, 5 slides – Xmatrx, 5 slides – Manual