CD19 is a cell surface molecule that interacts with the antigen receptor of B lymphocytes in order to reduce the threshold for antigen receptor-dependent stimulation. CD19 is expressed on folliculare dendritic cells and B cells. In fact, it is present on B cells from earliest recognizable B-cell lineage cells during development to B-cell blasts but it absent on maturation of B-cell to plasma cells. It primarily acts as a B cell co-receptor in conjunction with CD21 and CD81. CD19 has been observed in lymphomas and leukemias but often weak/negative in follicular lymphoma or diffuse target B-cell lymphoma. CD19 is well-suited for formalin-fixed paraffin-embedded tissues, flow cytomentry and western blotting technique. CD19 can provide useful diagnositic informationation for the study of B lymphoproliferative disorders
| Intended Use | IVD |
|---|---|
| Antibody Type | Monoclonal |
| Clone | EP169 |
| Source | Rabbit |
| Tissue Type/Cancer Type | Tonsil |
| Pack | 0.5 mL – Manual – Concentrate, 1 mL – Manual – Concentrate, 6 mL – Manual – RTU, 50 Tests – Automation – Xmatrx, 100 Tests – Automation – i6000, 160 Tests – Automation – Xmatrx, 5 slides – Xmatrx, 5 slides – Manual |
