Datasheet SDS

CD162, also known as P-Selectin Glycoprotein Ligand-1(PSGL-1) or SELPLG, is a 120 kDa mucin-like type I transmembrane glycoprotein found as a homodimer with two disulfide-linked subunits. It is expressed on activated endothelial cells, neutrophils, monocytes, platelets, macrophages/DC’s, most lymphocytes including NK and T cells but significantly low levels on B cells. CD162 is shown to be an important immune marker of T cell exhaustion in chronic viral infections and cancer.