CD133 also designated PROM1, Prominin-1 or AC133, is a 97 kDa stem cell antigen with 5 transmembrane domains. It is a pentaspan transmembrane glycoprotein expressed by immature hematopoietic stem cells but not mature blood cells. CD133 is expressed on primitive hematopoietic stem cells, progenitor stem cells, retinoblastoma, developing epithelium, hemangioblasts, neural stem cells and embryonic stem cells. It is also found on found on cancer cells, such as some leukemia cells and brain tumor cells. CD133 is frequently used as panel marker for blood stem cells, other stem cells, including cancer stem cells.
Intended Use: IVD
Antibody Type: Monoclonal
Clone: PROM/6316
Source: Mouse
Tissue Type/Cancer Type: Squamous Carcinoma Tissue