CD11c (ITGAX) belongs to the leukocyte integrin family of adhesion proteins. CD11c is expressed prominently on the plasma membranes of tissue macrophages, NK cells, monocytes, and most dendritic cells (DCs) . A lower level of expression is also observed on neutrophils as a result of its high level of expression on most DCs. An antibody to CD11c may aid in identification of lesions with histiocytic origin. It may also been used as a marker for hairy cell leukemia in paraffin embedded tissues .
Intended Use: IVD
Antibody Type: Monoclonal
Clone: EP157
Source: Rabbit
Tissue Type/Cancer Type: Tonsil