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Anti-CD117/c-Kit/SCF-Receptor

SKU: AR759GP Categories: , , ,
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Product Description

CD117 is a hematopoietic stem cell surface cytokine receptor protein of 145kDa. It is ?identified as CD117/p145kit. This rabbit polyclonal antibody does not interfere with the binding of SCF to c-kit. It precipitates both the unoccupied as well as the occupied form of c-kit. The binding of the stem cell factor (SCF) to the c-kit-encoded receptor tyrosine kinase (Type III) stimulates a variety of biochemical responses that culminate in cellular proliferation, migration, or survival. C-kit plays an important role in hematopoiesis, melanogenesis, and gametogenesis

Intended Use

IVD

Antibody Type

Polyclonal

Clone

Polyclonal

Source

Rabbit

Tissue Type/Cancer Type

Gist

Pack

0.5 mL – Manual – Concentrate, 1 mL – Manual – Concentrate, 6 mL – Manual – RTU, 50 Tests – Automation – Xmatrx, 100 Tests – Automation – i6000, 200 Tests – Automation – Xmatrx, 5 slides – Xmatrx, 5 slides – Manual