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Anti-CD105

SKU: AM441GP Categories: , , ,
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Product Description

CD105 protein (endoglin) is involved in cellular proliferation and hypoxia induction in angiogenic endothelial cells. It is a transforming growth factor (TGF) -beta1 and -beta3 receptor and modulates TGF-beta signaling by interacting with TGF-beta receptors I and/or II and hence driving tumor growth and metastasis. Endoglin (CD105) marker is better to identify proliferating endothelium involved in tumor angiogenesis than pan-endothelial markers such as CD31, CD34 , Factor VIII etc. It can be used as a marker for microvessel density measurement and also in tumor imaging

Intended Use

IVD

Antibody Type

Monoclonal

Clone

4G11

Source

Mouse

Tissue Type/Cancer Type

Uterus

Pack

0.5 mL – Manual – Concentrate, 1 mL – Manual – Concentrate, 6 mL – Manual – RTU, 50 Tests – Automation – Xmatrx, 100 Tests – Automation – i6000, 200 Tests – Automation – Xmatrx, 5 slides – Xmatrx, 5 slides – Manual