Menu

Anti-CD103

SKU: AN739GPE Categories: , , ,
Clear

Product Description

CD103 or Integrin ?E?7 is a human cell surface receptor integrin protein that is coded by the ITGAE gene. CD103 is usually expressed on T lymphocyte subset populations. The major ligand for CD103 or Integrin ?E?7 is E-cadherin present on the surface of epithelial cells and the cadherin and Integrin ?E?7 complex mediate migration, cell adhesion, and signalling for T lymphocyte localization. CD103 expression during malignancies increases, such as T-cell lymphomas and hairy cell leukaemia, 95% of intraepithelial CD8+ cells and 40% of mucosa associated T cells, whereas less than 2% of resting blood lymphocytes are CD103 positive

Intended Use

IVD

Antibody Type

Monoclonal

Clone

EP206

Source

Rabbit

Tissue Type/Cancer Type

Colon Ca

Pack

0.5 mL – Manual – Concentrate, 1 mL – Manual – Concentrate, 6 mL – Manual – RTU, 50 Tests – Automation – Xmatrx, 100 Tests – Automation – i6000, 200 Tests – Automation – Xmatrx, 5 slides – Xmatrx, 5 slides – Manual