Cathepsin K also designated as CTSK, CTSO, CTSO2, is a lysosomal cysteine protease belongs to the papain cysteine protease family. It is an important protease involved in bone remodeling and resorption by degrading type I collagen, osteopontin, and other bone matrix proteins. Cathepsin K expression is observed in bone, cartilage and skeletal muscle. Its expression is also seen in a significant fraction of human breast cancers, where it could contribute to tumor invasiveness.
Breast Carcinoma Tissue
6 mL (RTU), 10 mL (RTU), 1 mL(Conc.), 0.5 mL (Conc.), 50 tests – Xmatrx Elite, 160 tests – Xmatrx Elite, 5 slides – Manual, 5 slides – Xmatrx