Calponin is a 33 kD thin filament-associated protein that plays a role in regulation of smooth muscle contractility by anchoring myosin to actin. Monoclonal antibody to Calponin in combination with clones SMMS-1(anti-myosin heavy chain antibody) and h-CD (anti-Caldesmon antibody) could be used to distinguish benign and in-situ lesions from invasive carcinomas. Monoclonal antibody to Calponin reacts with vascular and visceral smooth muscle cells, myoepithelial cells in normal and benign human mammary gland, and certain stromal myofibroblasts.
| Intended Use | IVD |
|---|---|
| Antibody Type | Monoclonal |
| Clone | CALP |
| Source | Mouse |
| Tissue Type/Cancer Type | Breast Ca |
| Pack | 0.5 mL – Manual – Concentrate, 1 mL – Manual – Concentrate, 6 mL – Manual – RTU, 50 Tests – Automation – Xmatrx, 100 Tests – Automation – i6000, 160 Tests – Automation – Xmatrx, 5 slides – Xmatrx, 5 slides – Manual |
