Calponin is a smooth muscle specific, actin-, tropomyosin- and calmodulin-binding protein considered to be involved in regulation and modulation of contraction of actomyosin. Calponin antibody has been found to be useful as a marker for myoepithelial and basal lamina in differentiating microinvasive from in situ ductal carcinomas of the breast. Calponin antibody may also have applications in malignant myoepithelium and pleomorphic adenoma of salivary gland as well as a useful marker for fine needle aspirates of papillary breast lesions
Intended Use | IVD |
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Antibody Type | Monoclonal |
Clone | EP63 |
Source | Rabbit |
Tissue Type/Cancer Type | Pleomorphic Adenoma |
Pack | 0.5 mL – Manual – Concentrate, 1 mL – Manual – Concentrate, 6 mL – Manual – RTU, 50 Tests – Automation – Xmatrx, 100 Tests – Automation – i6000, 160 Tests – Automation – Xmatrx, 5 slides – Xmatrx, 5 slides – Manual |