The c-Myc (62 kDa) is an oncogenic transcription factor located on human chromosome 8q24. It is implicated in cycle progression, apoptosis, cellular transformation and angiogenesis. C-Myc specifically associates with a basic region helix-loophelix leucine zipper motif (bHLH-Zip) protein, designated Max and acts as a potent transcriptional activator by binding to DNA. Amplification of this oncogene have been associated with tumors of different origins such as colorectal, prostatic, head and
neck, thyroidal, pulmonary, gastric, gallbladder, hepatic, oral, ocular, nasopharyngeal, mammary, ovarian, endometrial, endocrine, as well as hematopoietic neoplasms.
| Intended Use | IVD |
|---|---|
| Antibody Type | Monoclonal |
| Clone | EP121 |
| Source | Rabbit |
| Tissue Type/Cancer Type | Intestinal Adenocarcinoma |
| Pack | 6 mL (RTU), 100 Tests – Automation – i6000, 1 mL(Conc.), 0.5 mL (Conc.), 160 tests – Xmatrx Elite, 50 tests – Xmatrx Elite, 5 slides ? Xmatrx, 5 slides ? Manual |
