Anti-c-Kit / CD117

$250.00$1,000.00

CD117 is a proto-oncogene, meaning that overexpression or mutations of this protein can lead to cancer. Seminomas, a subtype of testicular germ cell tumors. Member of the Tyrosine Kinase Receptor (TKRs) and highly homologous to receptor PDF and CSF-1. Activation of c-Kit tyrosine kinase by SCF (Stem Cell factor) leads to autophosphorylation and association of c-Kit with substrate PI3K. CD117 is a marker for Mast cell and gastrointerstinal stroma tumor.
SKU: AN818GPE
Intended Use: IVD
Antibody Type: Monoclonal
Clone: EP10
Source: Rabbit
Tissue Type/Cancer Type: Stomach