The c-erbB-3 gene product is a 180kD transmembrane glycoprotein showing tyrosine kinase activity. It belongs to a family of growth receptors that show structural similarity to epidermal growth factor receptor (EGFR) and the c-erbB-2 proteins. The c-erbB-3 protein is widely expressed in digestive, urinary and respiratory tracts, the circulatory systems, female and male reproductive system but not in hematopoetic system. c-erbB-3 protein has also been seen to be overexpressed in some tumors including those of the breast, stomach, pancreas, colon and ovary
Intended Use | IVD |
---|---|
Antibody Type | Monoclonal |
Clone | RTJ1/A2 |
Source | Mouse |
Tissue Type/Cancer Type | Breast Ca |
Pack | 0.5 mL – Manual – Concentrate, 1 mL – Manual – Concentrate, 6 mL – Manual – RTU, 50 Tests – Automation – Xmatrx, 100 Tests – Automation – i6000, 160 Tests – Automation – Xmatrx, 5 slides – Xmatrx, 5 slides – Manual |