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Anti-c-erbB-2 (Her-2/neu)

SKU: AM134GPE Categories: , , ,
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Product Description

Her-2/neu (c-erb-B2) gene product is a 185 kDa tyrosine kinase transmembrane glycoprotein. Her-2/neu belongs to erb gene family. Her-2/neu has been linked to prognosis and response to therapy with the anti-HER-2-humanized monoclonal antibody. The antibody CB11 is directed against the internal domain of this oncoprotein. Approximately 20-30% cases of breast cancer show an amplification and/or overexpression of Her-2 in tumor cells. Since there is an availability of the target therapy to Her-2 Neu positive tumors, the lab testing of Her-2/neu in breast carcinoma becomes very important in patient care

Intended Use

IVD

Antibody Type

Monoclonal

Clone

CB11

Source

Mouse

Tissue Type/Cancer Type

Breast Ca

Pack

0.5 mL – Manual – Concentrate, 1 mL – Manual – Concentrate, 6 mL – Manual – RTU, 50 Tests – Automation – Xmatrx, 100 Tests – Automation – i6000, 200 Tests – Automation – Xmatrx, 5 slides – Xmatrx, 5 slides – Manual