Bax protein is identified as promoter of apoptosis.The inhibitor proteins of apoptosis are known to form homodimers or heterodimers with the apoptosis promoter proteins. Cells displaying higher levels of Bax relative to Bcl-2 generally undergo apoptosis. The override of apoptotic control is suspected to cause or contribute to some forms of carcinogenesis. This antibody will detect the a , ß , and d isoforms of Bax protein.
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