BLA.36 is a developmentally regulated 36 kDa antigen expressed on the plasma membrane of B lymphocytes, ReedSternberg, and mononuclear Hodgkin?s cells. The anti-BLA.36 antibody recognizes all four subtypes of Hodgkin’s disease. It also gives strong staining of B cell lymphomas including follicular center cell lymphomas (large and small cell types), mantle zone lymphomas, and immunoblastic lymphomas. No reactivity of anti-BLA.36 is found in normal epithelial cells, including adrenal gland, breast, colon, lung, salivary gland, skin, stomach and their malignant counterparts. Anti-BLA.36 can be used to distinguish Reed-Sternberg cells and some Bcell lymphomas from other malignant cells.
| Intended Use | IVD |
|---|---|
| Antibody Type | Monoclonal |
| Clone | A27-42 |
| Source | Mouse |
| Tissue Type/Cancer Type | Hodgkin |
| Pack | 0.5 mL – Manual – Concentrate, 1 mL – Manual – Concentrate, 6 mL – Manual – RTU, 50 Tests – Automation – Xmatrx, 100 Tests – Automation – i6000, 160 Tests – Automation – Xmatrx, 5 slides – Xmatrx, 5 slides – Manual |
