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Anti-Anti-IL-1a, Clone IL1A/3981

SKU: AMA98GP Categories: , , ,
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Product Description

There are two forms of interleukin-1 exists and designated as IL-1α and IL-1β. Interleukin 1α (IL-1α) and IL-1β are equally potent inflammatory cytokines that activate the inflammatory process, and their deregulated signaling causes devastating diseases manifested by severe acute or chronic inflammation. Although much attention has been given to understanding the biogenesis of IL-1β, the biogenesis of IL-1α and its distinctive role in the inflammatory process remain poorly defined. IL-1 plays a critical role in the regulation of immune response and inflammation, acting as an activator of T and B lymphocytes and natural killer (NK) cells. IL-1 has also been implicated in several pathological conditions including rheumatoid arthritis, inflammatory bowel disease and atherosclerosis.

Intended Use

IVD

Antibody Type

Monoclonal

Clone

IL1A/3981

Source

Mouse

Tissue Type/Cancer Type

Colon tissue

Pack

6 mL (RTU), 100 Tests – Automation – i6000, 1 mL(Conc.), 0.5 mL (Conc.), 160 tests – Xmatrx Elite, 50 tests – Xmatrx Elite, 5 slides – Xmatrx, 5 slides – Manual