Annexin A1, also designated as Annexin I, calpactin II, p35 and lipocortin I, is a ~ 40 kDa protein belongs to the family of Calcium-dependent phospholipid-binding proteins “Annexins”. It is a pleiotrophic protein and inhibits phospholipase A2 activity which is required for the biosynthesis of the potent mediators of inflammation, prostaglandins and leukotrienes. It is expressed abundantly on peripheral blood leukocytes and the antibody to Annexin A1 is used to differentiate hairy cell leukemia from other B-cell lymphomas.
Intended Use | IVD |
---|---|
Antibody Type | Monoclonal |
Clone | ANXA1/3566 |
Source | Mouse |
Tissue Type/Cancer Type | Testis Tissue |
Pack | 6 mL – Manual – RTU, 100 Tests – Automation – i6000, 1 mL – Manual – Concentrate, 0.5 mL – Manual – Concentrate, 50 Tests – Automation – Xmatrx, 50 tests – NanoVIP®, 160 Tests – Automation – Xmatrx, 5 slides – Xmatrx, 5 slides – Manual |