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Anti-Anaplastic Lymphoma Kinase (ALK)

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Product Description

Anaplastic lymphoma kinase(ALK) belongs to receptor tyrosine kinases, it is involved in Chromosomal translocations found in different diseases such as anaplastic large cell lymphomas (ALCLs) and non small-cell lung cancer (NSCLC). The constitutively expressing active fusion proteins are accountable for most of anaplastic large cell non-Hodgkin?s lymphomas. The EML4-ALK fusion gene is responsible for approximately 3-5% of NSCLC. EML4-ALK-rearrangement in NSCLC is exclusive and not found in EGFR- or KRAS-mutated

Intended Use

IVD

Antibody Type

Monoclonal

Clone

SP144

Source

Rabbit

Tissue Type/Cancer Type

Anaplastic Lymphoma

Pack

0.5 mL – Manual – Concentrate, 1 mL – Manual – Concentrate, 6 mL – Manual – RTU, 50 Tests – Automation – Xmatrx, 100 Tests – Automation – i6000, 200 Tests – Automation – Xmatrx, 5 slides – Xmatrx, 5 slides – Manual