Anaplastic lymphoma kinase(ALK) belongs to receptor tyrosine kinases, it is involved in Chromosomal translocations found in different diseases such as anaplastic large cell lymphomas (ALCLs) and non small-cell lung cancer (NSCLC). The constitutively expressing active fusion proteins are accountable for most of anaplastic large cell non-Hodgkin?s lymphomas. The EML4-ALK fusion gene is responsible for approximately 3-5% of NSCLC. EML4-ALK-rearrangement in NSCLC is exclusive and not found in EGFR- or KRAS-mutated
| Intended Use | IVD |
|---|---|
| Antibody Type | Monoclonal |
| Clone | SP144 |
| Source | Rabbit |
| Tissue Type/Cancer Type | Anaplastic Lymphoma |
| Pack | 0.5 mL – Manual – Concentrate, 1 mL – Manual – Concentrate, 6 mL – Manual – RTU, 50 Tests – Automation – Xmatrx, 100 Tests – Automation – i6000, 160 Tests – Automation – Xmatrx, 5 slides – Xmatrx, 5 slides – Manual |
