Actinins are actin-binding proteins of 100 kD. Alpha-Actinin is a F-actin cross-linking protein thought to anchor actin to a variety of intracellular structures. Alpha-Actinin is found in stress fibers and adhesion plaques in non-muscle cells and in Z-discs and their homologues in muscle cells. Anti-Alpha-Actinin may stain erythrocyte membranes, and reacts with characteristic particulates in congenital nemaline myopathy.
|Tissue Type/Cancer Type|
0.5 mL – Manual – Concentrate, 1 mL – Manual – Concentrate, 6 mL – Manual – RTU, 50 Tests – Automation – Xmatrx, 100 Tests – Automation – i6000, 200 Tests – Automation – Xmatrx, 5 slides – Xmatrx, 5 slides – Manual