Alpha 1-Antichymotrypsin (AACT) also known as cell growth-inhibiting gene 24/25 protein and Serpin A3, is a 65-76kDa alpha globulin glycoprotein belongs to the Serpin family. It inhibits the activity of proteases by cleaving them into a different shape or conformation. Deficiency of this protein has been associated with liver disease and variations in this protein's sequence have been implicated in Alzheimer's disease. The Alpha 1-Antivhymotrypsin antibody reacts with histiocytes and widely used to identify tumors derived from histiocytes. Its expression is also seen in acinar tumors of the pancreas and salivary gland.
6 mL (RTU), 100 Tests – Automation – i6000, 1 mL(Conc.), 0.5 mL (Conc.), 50 tests – Xmatrx Elite, 160 tests – Xmatrx Elite, 5 slides – Manual, 5 slides – Xmatrx