Adipophilin (ADFP, adipocyte differentiation-related protein) belongs to the perilipin family associated with lipid globule surface membranes and intracellular lipid storage droplets in various normal cells. It is a major constituent of the globule surface and involved in the development and maintenance of adipose tissue. It is present in the cytoplasm of a wide range of cultured cell lines and tissues, including fibroblasts, endothelial and epithelial cells, lactating mammary glands, the adrenal cortex, Sertoli & Leydig cells, and hepatocytes in alcoholic liver cirrhosis. Anti-Adipophilin is considered a useful marker of cytoplasmic lipids, sebocytes, and lipid accumulation, and can be used to identify sebaceous lesions and carcinomas.
|Tissue Type/Cancer Type||
6 mL (RTU), 100 Tests – Automation – i6000, 1 mL(Conc.), 0.5 mL (Conc.), 160 tests – Xmatrx Elite, 50 tests – Xmatrx Elite, 5 slides – Xmatrx, 5 slides – Manual