DatasheetSDS

Adenoviruses are simple DNA-containing viruses that multiply in the cell nucleus. They induce latent infections in tonsils, adenoids and other lymphoid tissue of man, causing either inapparent or limited illnesses that are followed by complete recovery and persistent type-specific immunity. Most individuals are infected with one or more adenovirus before the age of 15. Approximately 50-80% of tonsils and adenoids removed surgically show adenovirus infection. This antibody is designed for the specific immunohistochemical localization of adenovirus. Monoclonal antibodies directed against viruses allow for the rapid identification of viral infections in tissues. The advantages of identifying viruses immunohistologically are twofold. First, this method decreases the time required for microbial identification by viral culture, and second, this method may demonstrate virus in tissues in which characteristic cytopathic effects have not yet developed and are therefore not detectable by morphological studies alone.