Actin, a major component of the cytoskeleton, is a globular protein about 5 nm in diameter and is composed of one polypeptide chain with a mass of approximately 47 kD. This antibody recognizes alpha actin of skeletal, cardiac and smooth muscle cells and gamma actin from smooth muscle cells and will stain the cytoplasm in these cells. It is non-reactive with other mesenchymal cells and all epithelial cells except for myoepithelium. It can thus be used as a marker for leiomyomas, leiomyosarcomas, rhabdomyomas and rhabdomyosarcomas.
|Tissue Type/Cancer Type|
0.5 mL – Manual – Concentrate, 1 mL – Manual – Concentrate, 6 mL – Manual – RTU, 50 Tests – Automation – Xmatrx, 100 Tests – Automation – i6000, 200 Tests – Automation – Xmatrx, 5 slides – Xmatrx, 5 slides – Manual