Adrenocorticotropic hormone (ACTH or Corticotropin) is a polypeptide tropic hormone produced and secreted by the anterior pituitary gland. It is an important component of the hypothalamic-pituitary-adrenal axis and is often produced in response to biological stress (along with corticotrophin-releasing hormone from the hypothalamus). Its principal effects are increased production of androgens and as its name suggests, cortisol from the adrenal cortex. Ab-1 is excellent for staining of routine formalin-fixed, paraffin-embedded tissues. It labels corticotrophs in the adenohypophysis and is useful in the classification of pituitary adenomas
| Intended Use | IVD |
|---|---|
| Antibody Type | Monoclonal |
| Clone | AH26 |
| Source | Mouse |
| Tissue Type/Cancer Type | Pituitary |
| Pack | 0.5 mL – Manual – Concentrate, 1 mL – Manual – Concentrate, 6 mL – Manual – RTU, 50 Tests – Automation – Xmatrx, 100 Tests – Automation – i6000, 160 Tests – Automation – Xmatrx, 5 slides – Xmatrx, 5 slides – Manual |
