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Anti-β-Amyloid
SKU: AMC27GP Categories: , ,

Beta amyloid (also known as Amyloid β or Aβ) is a 40–43 amino acid peptide cleaved from transmembrane amyloid precursor protein (APP) by proteases, beta-secretase (BACE-1) and gamma-secretase. Cleaved Aβ peptides [1-40], [1-42], [1-43] are extracellularly accumulated to form aggregates, insoluble oligomers and protofibrils called as neuritic plaques. The neuritic plaques are found in the brains of patients with Alzheimer’s disease (AD) and research indicates that intraneuronal beta amyloid accumulation may be an important proximal neurotoxic event in the pathogenesis of Alzheimer’s disease.

Intended Use

IVD

Antibody Type

Monoclonal

Clone

B-4

Source

Mouse

Tissue Type

Kidney Carcinoma Tissue

Pack

6 mL (RTU), 10 mL (RTU), 1 mL(Conc.), 0.5 mL (Conc.), 50 tests – Xmatrx Elite, 160 tests – Xmatrx Elite, 5 slides – Manual, 5 slides – Xmatrx