Nucleic Acid Retrieval

Nucleic Acid Retrieval is an effective way of unmasking DNA in formalin-fixed, paraffin-embedded tissue sections using microwave heating. The Nucleic Acid Retrieval solution breaks the formalin induced cross-linking bonds between DNA and proteins, as well as protein-protein cross-linking thereby allowing better penetration of probes and accessibility of DNA for binding. Nucleic Acid Retrieval (NAR-1) is recommended instead of Proteinase K when DNA targeting probes are used.

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