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Anti-P16 for Cervical Tumor Diagnosis

BioGenex presents Anti-P16 antibody for Cervical tumor diagnosis. p16 INK4A, also designated as CDKN2A or p16, is an important cell cycle regulator and acts as a tumor suppressor that inhibits the catalytic activity of the Cdk4/cyclin D complex. P16 binds to CDK4 and inhibiting its kinase ability, so that it cannot phosphorylate the retinoblastoma tumor suppressor (RB). 
Mutations in the gene leads to inactivation of p16 protein which has been associated with an increased risk of cancer and are often observed in primary tumors and in cancer cell lines. Aberrant p16 INK4a have been reported among melanomas, gliomas, esophageal, pancreatic, lung, and urinary bladder carcinomas.
BioGenex offers ready-to-use (RTU) & concentrated forms of antibodies for both manual & automated systems which are best-in-class for clinicopathological diagnosis & drug discovery. It enables pathologists & clinicians to precisely diagnose and improve life expectancy.